Doxycycline is a bacteriostatic antibiotic from the group of tetracycline. It has a broad action and penetrates inside the cells of bacteria. Affecting the intracellular agents of infection, the antibiotic quickly reduces the symptoms of the infection and improves health of a patient.
Doxycycline is active as to most dangerous infectious diseases: venereal granuloma, malaria, trachoma, amoebic dysentery, chlamydia, brucellosis, plague, cholera vibrio, etc.
It differs from most tetracyclines because it does not affect intestinal flora and seldom causes dysbiosis. Doxycycline does not normally affect the useful microorganisms, and therefore it is allowed for the long-term use. Moreover, unlike tetracycline and oxytetracycline, it has a higher therapeutic efficiency appearing in the treatment with low doses.
The use of Doxycycline gives the results in the treatment of the following infectious diseases:
- Pharyngitis, acute and chronic bronchitis, tracheitis, bronchopneumonia, abscess of the lung and other respiratory diseases
- Otitis, tonsillitis, sinusitis and other infections of the ear, throat, nose
- Cystitis, pyelonephritis, prostatitis, urethritis, urogenital mycoplasmosis, endometritis and genitourinary system infections not listed in this article
- Abscesses, furunculosis, panaritium, infected burns, wounds
Doxycycline is recommended patients over 12 years old who have the body weight more than 45 kg.
The treatment of any infection is started from the first day and from the high dose, and then Doxycycline is used in lower doses. A standard dosing is 200 mg of Doxycycline in the first day (a pill 100 mg with the interval of 12 hours), and 100 mg per day is used starting from the second day.
But if severe infections (syphilis, gonorrhea, urethritis), a dose of 300 mg may be prescribed in the first day, and then 200 mg are used every day within 7-10 days.
The treatment usually takes up to 2 weeks but even medical case is individual, and therefore a length of the treatment depends on the patient’s reaction to the action of the antibiotic.
To treat acne, Doxycycline may be used for up to 12 weeks.
- As other tetracyclines, Doxycycline is not recommended children under 12 years old. The antibiotics of this group may form indissolvable compounds with calcium in bony skeleton, enamel and dental tissues
- Do not take Doxycycline in case of the renal failure and diseases of the hematologic system
- Pregnant women should restrain from the use of the antibiotic. And breast-feeding women should use baby formula during the treatment
- If you were prescribed a combined treatment with the use of the several antibiotics, avoid the use of Doxycycline with penicillin, cephalosporins providing a bactericidal action. Any bactericidal antibiotics lower therapeutic functions of Doxycycline
An overdose of Doxycycline is accompanied by severe side effects in the gastro-intestinal tract: vomiting, flatulency, stomachache, gastritis, esophagitis, and diarrhea.
Moreover, a patient may have candidiasis, dysfunction of liver and allergic reaction. Therefore it is very important to not exceed the maximal daily dose of Doxycycline 300 mg, if a doctor did not prescribe another dose.