Generic Name: Esomeprazole
Dosage Package: 40 mg, 20 mg

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Nexium is prescribed patients during an attack of the ulcer of stomach and duodenum. The medicine has a unique ability to reduce synthesis of the hydrochloric acid and accelerate a healing of ulcers in the mucous membrane of the gastro-intestinal tract.

A decrease of the acidity of the gastric juice happens due to the active ingredient Esomeprazole. This ingredient blocks a proton pump, a set of enzymes and glands that take part in the synthesis of the hydrochloric acid. Due to the reduction of the acidity in the stomach, the irritation of the walls is reduced, and a protective coat is formed that accelerates the healing of the ulcers.

Nexium may be used not only during the attack of the ulcers but also during other diseases caused by the excessive secretion of the hydrochloric acid: reflux esophagitis, peptic ulcers during the use of the non-steroid anti-inflammatory drugs, gastric ulcers associated with helicobacter pylori, and others.

After the peroral use of Nexium, its active ingredients are quickly digested by the body and start working in 1-2 hours. In fact, the changes may be seen only in a couple of days after the started treatment.

At first, acute stomachache is gone, bleedings are stopped, heartburn disappears, and then stomachache completely passes, bloating disappears, and a digestion process is restored. Bear in mind that Nexium is just an adjunct product for the treatment of the gastric ulcer. Diet plays a great role in the treatment of this disease.


Product Instruction


A dose of Nexium depends on a functional disorder in the gastro-intestinal tract. As every disease is manifested in different ways, the treatment varies.

For example, in case of the attack of ulcer of stomach and duodenum, it is better to take Nexium in the dose of 10 mg 2 times per day. The first dose of 10 mg should be taken in the morning before breakfast, and another dose – 10 mg is taken before sleeping. Hydrochloric acid is produced at night as well, and as there is no food in the stomach, it will eat the walls of the mucous membrane.

To prevent peptic ulcers associated with the use of NSAIDS, 20 mg of Nexium will be enough once per day.

To treat reflux-esophagitis, Nexium is also used once per day but the dose should be 40 mg per day.

A length of the treatment is individual. In some cases, 2-3 weeks will be enough for a complete recovery of the mucous membrane of the gastro-intestinal tract, and some patients will need 3 months and the use of Nexium with other medicines.




  • Nexium may be taken at any age by means of its good tolerance. The only restriction is children under 1 year old
  • The medicine is carefully prescribed during severe renal failure. The medicine is seldom used during this disease, and so it is difficult to give some recommendations
  • A prescription of Nexium during pregnancy is possible but only under doctor’s supervision


Overdose Symptoms


The overdose with Nexium is unlikely even during the use of high doses. But due to the high sensation to Esomeprazole, some patients may have side effects in the gastro-intestinal tract, fatigue, and change of the body weight. Any side effects including the overdose symptoms should be discusses with a doctor.


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