Generic Name: Bupropion
Dosage Package: 150 mg

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Zyban is one of the first drugs for the treatment of nicotine addiction and does not have nicotine. The mechanism of the action is not based on nicotine replacement therapy. It blocks a desire to smoke by means of the changed natural internal processes.

An active ingredient Bupropion is responsible for the action of Zyban. This ingredient is an antidepressant and regulates a concentration of some neurotransmitters in the brain. First of all, this ingredient blocks a reuptake of dopamine, a satisfaction hormone.

The mechanism of the action of Zyban is very simple. When a person gives up smoking, a withdrawal syndrome occurs (the side effects influence on the psychological and physiological state). Most people do not cope with the psychological tension and return to a bad habit.

Taking Zyban increases the level of dopamine, and so a human does not have a psychological or physiological discomfort while quitting smoking. And if a person smokes, a level of the satisfaction hormone is not changed, and so no positive emotions appear. This way, a smoker does not want to smoke and easily gives up a bad habit. The treatment is based on changing the attitude to cigarettes, and therefore the effect from the therapy is kept for many years.

Product Instruction

If you decided to give up smoking, be ready for a long-term therapy. Zyban is effective only during a long-term treatment. The longer you take the pills, the more chances to quit smoking. The medical tests have proved that more than 27% of patients stated an easy quitting smoking in 7 weeks of the treatment. The longer the therapy is, the more people give up smoking.

The treatment starts from the minimal daily dose of Zyban 150 mg. A person continues smoking within the first week and takes a pill per day. Starting from the 8th day, it is necessary to completely stop smoking and increase a dose of Zyban up to 300 mg per day. A daily dose may be divided into 2 parts, and a pill will be used in the morning, and another pill will be taken in the afternoon. The interval between the use of the pills should be at least 8 hours.

In 7-12 weeks, a medical examination is done, and the efficiency of the therapy is checked. The treatment is continued, if a patient still has a desire to smoke.


  • Zyban is not prescribed people suffering from epilepsy, acute mental disorders or organic diseases of the brain
  • Avoid the use of the drug if you are taking MAO inhibitors. If you want to start the use of Bupropion, finish the use of the MAO inhibitors 2 weeks before the therapy of the nicotine addiction
  • Zyban is not prescribed during alcohol, narcotic or medical intoxication. Clean the body and then start the treatment

Overdose Symptoms

The overdose with Zyban is not required. First of all, the therapy should be stopped gradually. Secondly, medical symptoms of the overdose are very dangerous.

The obvious symptoms of the overdose are: tachycardia, arterial hypertension, agitation, nausea and vomiting, delirium and seizures, auditory and visual hallucinations. There is no special treatment for these symptoms. It is necessary to see a doctor as soon as possible and get a symptomatic treatment and control of all functions of the body.


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